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Physicians should consider an alternative medication or advise the patient to discontinue breastfeeding. Reported cases show biliary atresia in infants who were exposed to amphetamine in utero during the second and third trimesters.Īmphetamine should not be prescribed to nursing women as it is excreted in human breast milk. Reports exist of increased risk of premature delivery and low birth weight in infants born to mothers with amphetamine dependence as amphetamine crosses the placenta. Use during pregnancy only if the potential maternal benefit outweighs the potential fetal risk.
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The American Academy of Pediatrics rates amphetamines as drugs of abuse for which there are reports of adverse effects on the infant during breastfeeding.Ĭonsider potential risks and benefits before prescribing amphetamines during pregnancy and breastfeeding. Potential benefits may warrant use in women who are pregnant.) In the pediatric population, the immediate-release tablet is recommended for patients three years of age or older, and the extended-release capsule can be prescribed to patients six years or older.Īmphetamines are Pregnancy Category C (prior to 2015) (Category C Animal reproduction studies have shown an adverse effect on the fetus, but no adequate and well-controlled studies in humans. Amphetamines, along with other remedial measures such as psychological, educational, and social, are prescribed to manage patients with symptoms like distractibility, short attention span, hyperactivity, and impulsivity. However, another study showed conflicting results, as the mean scores on the Fugl-Meyer motor scale were not significant for the amphetamine group compared with the placebo group.Īmphetamine/dextroamphetamine is used off-label by college students for memory enhancement, test-taking ability, and study marathons.įDA-approved clinical uses for dextroamphetamine/amphetamine:Īttention Deficit Disorder with Hyperactivityĭextroamphetamine/amphetamine is FDA-approved for adult and pediatric (ages 3 to 16 years) populations. in 1988 shows that amphetamine use in patients with ischemic stroke improved motor function compared with patients undergoing physical therapy alone.